Package: PKbioanalysis 0.2.0

Omar Elashkar

PKbioanalysis: Pharmacokinetic Bioanalysis Experiments Design and Exploration

Automate pharmacokinetic/pharmacodynamic bioanalytical procedures based on best practices and regulatory recommendations. The package impose regulatory constrains and sanity checking for common bioanalytical procedures. Additionally, 'PKbioanalysis' provides a relational infrastructure for plate management and injection sequence.

Authors:Omar Elashkar [aut, cre]

PKbioanalysis_0.2.0.tar.gz
PKbioanalysis_0.2.0.zip(r-4.5)PKbioanalysis_0.2.0.zip(r-4.4)PKbioanalysis_0.2.0.zip(r-4.3)
PKbioanalysis_0.2.0.tgz(r-4.5-any)PKbioanalysis_0.2.0.tgz(r-4.4-any)PKbioanalysis_0.2.0.tgz(r-4.3-any)
PKbioanalysis_0.2.0.tar.gz(r-4.5-noble)PKbioanalysis_0.2.0.tar.gz(r-4.4-noble)
PKbioanalysis_0.2.0.tgz(r-4.4-emscripten)PKbioanalysis_0.2.0.tgz(r-4.3-emscripten)
PKbioanalysis.pdf |PKbioanalysis.html✨
PKbioanalysis/json (API)
NEWS

# Install 'PKbioanalysis' in R:

install.packages('PKbioanalysis', repos = c('https://omarashkar.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/omarashkar/pkbioanalysis/issues

On CRAN:

4.40 score 4 scripts 162 downloads 18 exports 99 dependencies

Last updated 5 months agofrom:142ed84472. Checks:1 OK, 8 NOTE. Indexed: yes.

Target	Result	Latest binary
Doc / Vignettes	OK	Mar 04 2025
R-4.5-win	NOTE	Mar 04 2025
R-4.5-mac	NOTE	Mar 04 2025
R-4.5-linux	NOTE	Mar 04 2025
R-4.4-win	NOTE	Mar 04 2025
R-4.4-mac	NOTE	Mar 04 2025
R-4.4-linux	NOTE	Mar 04 2025
R-4.3-win	NOTE	Mar 04 2025
R-4.3-mac	NOTE	Mar 04 2025

Exports:add_blank add_cs_curve add_DB add_qcs add_samples add_samples_c add_suitability build_injec_seq combine_injec_lists combine_plates download_sample_list generate_96 make_calibration_study make_metabolic_study plate_app plate_metadata register_plate write_injec_seq

Dependencies:backports base64enc bit bit64 bsicons bslib cachem checkmate cli clipr colorspace commonmark cpp11 crayon crosstalk DBI DiagrammeR digest dplyr DT duckdb evaluate fansi farver fastmap fontawesome fs generics ggforce ggplot2 glue gtable highr hms htmltools htmlwidgets httpuv igraph isoband jquerylib jsonlite knitr labeling later lattice lazyeval lifecycle magrittr MASS Matrix memoise mgcv mime munsell nlme pillar pkgconfig polyclip prettyunits progress promises purrr R6 rappdirs RColorBrewer Rcpp RcppEigen readr rhandsontable rlang rmarkdown rstudioapi sass scales shiny shinyalert shinyjs shinyWidgets sourcetools stringi stringr systemfonts tibble tidyr tidyselect tinytex tweenr tzdb units utf8 uuid vctrs viridisLite visNetwork vroom withr xfun xtable yaml

PKbioanalysis overview

Omar Elashkar

Rendered fromPKbioanalysis_overview.Rmdusingknitr::rmarkdownon Mar 04 2025.

Last update: 2024-10-02
Started: 2024-09-09

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Subsetting method for MultiPlate	[[,MultiPlate-method
Add blank to the plate Can be either double blank (DB), CS0IS+ or CS1IS-	add_blank
Add calibration curve to the plate	add_cs_curve
Add double blank (DB) to a plate	add_DB
Add quality control samples to the plate	add_qcs
Add unknown samples to a plate	add_samples
Cartesian product of sample factors to a plate	add_samples_c
Add suitability sample to the plate	add_suitability
Create Injection Sequence	build_injec_seq
Create Injection Sequence from MultiPlate (Multiple Plates)	build_injec_seq,MultiPlate-method
Create Injection Sequence from PlateObj (Single Plate)	build_injec_seq,PlateObj-method
Create Sample List with rigorous design	combine_injec_lists
Combine plates in MultiPlate object	combine_plates
Download sample list from database to local spreadsheet	download_sample_list
Generate 96 Plate Generate a typical 96 well plate. User need to specify the empty rows which a going to be used across the experiment.	generate_96
Length method for MultiPlate	length,MultiPlate-method
Create a calibration study with calibration standards and QCs	make_calibration_study
Create a metabolic study layout	make_metabolic_study
bioanalytic_app	plate_app
Set plate description	plate_metadata
Plotting 96 well plate	plot.PlateObj
Register a plate This will save the plate to the database	register_plate
Register a multiple plates at once	register_plate,MultiPlate-method
Register a plate This will save the plate to the database	register_plate,PlateObj-method
Export injection sequence to vendor specific format	write_injec_seq